Primary Lateral Sclerosis is
a muscular nervous disorder

where the motor nerve cells to decline. PLS leads to stiffness and spasticity of the muscles in the mouth, legs and arms.

It's time to stop PLS

At PLS there is a problem with
the central motor neurons

These are at the top of the brain, in the cerebral cortex. Its foothills run through the brainstem and spinal cord.

It's time to stop PLS

At PLS, the complaints
begin mostly in the legs

However, PLS can also start in the muscles for speaking or muscles of the arms.

It's time to stop PLS

About the PLS website

Jos Lotz has been diagnosed with PLS since 1999. Since 2000 he has made this personal website because very little was known about the PLS condition.
On this website he describes the symptoms and his personal experiences with this.
By sharing his experiences, he hopes that fellow sufferers will find recognition and recognition here.